RGS13 antibody

Catalog No. ABIN2460852

The Rabbit Polyclonal anti-RGS13 antibody (ABIN2460852) specifically detects RGS13 in WB and ELISA. The antibody is reactive with Human and Dog samples.

Quick Overview for RGS13 antibody (ABIN2460852)

Target: RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RGS13 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RGS13.

Application Details

Application Notes: RGS13 antibody can be used for detection of RGS13 by ELISA at 1:62500. RGS13 antibody can be used for detection of RGS13 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store RGS13 antibody at -20 °C.

Target Details for RGS13

Target: RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

Alternative Name: RGS13

Background: The protein encoded by RGS13 is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown.

Molecular Weight: 17 kDa, 19 kDa

Gene ID: 6003

NCBI Accession: NP_658912

UniProt: O14921

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling