ACCN4 antibody

Catalog No. ABIN2461166

Product Details anti-ACCN4 Antibody

Target: ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))

Reactivity: Human, Rat, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACCN4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ACCN4.

Application Details

Application Notes: ACCN4 antibody can be used for detection of ACCN4 by ELISA at 1:500. ACCN4 antibody can be used for detection of ACCN4 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ACCN4 antibody at -20 °C.

Target Details for ACCN4

Target: ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))

Alternative Name: ACCN4 (ACCN4 Products)

Synonyms: ACCN4 antibody, BNAC4 antibody, Accn4 antibody, Spasic antibody, acid sensing ion channel subunit family member 4 S homeolog antibody, acid sensing ion channel subunit family member 4 antibody, acid-sensing (proton-gated) ion channel family member 4 antibody, asic4.S antibody, ASIC4 antibody, Asic4 antibody

Background: ACCN4 belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. ACCN4 is predominantly expressed in the pituitary gland, and might be a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder.

Molecular Weight: 46 kDa

Gene ID: 55515