TRIP13 antibody

Catalog No. ABIN2461196

The Rabbit Polyclonal anti-TRIP13 antibody is suitable to detect TRIP13 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for TRIP13 antibody (ABIN2461196)

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRIP13 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIP13.

Application Details

Application Notes: TRIP13 antibody can be used for detection of TRIP13 by ELISA at 1:12500. TRIP13 antibody can be used for detection of TRIP13 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TRIP13 antibody at -20 °C.

Target Details for TRIP13

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Alternative Name: TRIP13

Background: The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins.

Molecular Weight: 49 kDa

Gene ID: 9319

NCBI Accession: NP_004228

UniProt: Q15645