TRIM23 antibody

Catalog No. ABIN2461638

The Rabbit Polyclonal anti-TRIM23 antibody (ABIN2461638) specifically detects TRIM23 in WB and ELISA. The antibody is reactive with Human, Rat, Mouse and Dog samples.

Quick Overview for TRIM23 antibody (ABIN2461638)

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Reactivity: Human, Rat, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM23 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRIM23 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIM23.

Application Details

Application Notes: TRIM23 antibody can be used for detection of TRIM23 by ELISA at 1:62500. TRIM23 antibody can be used for detection of TRIM23 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TRIM23 antibody at -20 °C.

Target Details for TRIM23

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Alternative Name: TRIM23

Background: TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.

Molecular Weight: 61 kDa, 64 kDa, 64 kDa

Gene ID: 373

NCBI Accession: NP_150231