ZNF259 antibody

Catalog No. ABIN2461709

Product Details anti-ZNF259 Antibody

Target: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF259 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF259.

Application Details

Application Notes: ZNF259 antibody can be used for detection of ZNF259 by ELISA at 1:312500. ZNF259 antibody can be used for detection of ZNF259 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZNF259 antibody at -20 °C.

Target Details for ZNF259

Target: ZNF259 (znf259) (Zinc Finger Protein 259 (znf259))

Alternative Name: ZNF259 (znf259 Products)

Synonyms: RGD1562173 antibody, zpr1 antibody, ZNF259 antibody, ZPR1 antibody, Zfp259 antibody, fc17g10 antibody, si:rp71-56i13.4 antibody, wu:fc17g10 antibody, zgc:56478 antibody, AI303781 antibody, Znf259 antibody, ZPR1 zinc finger antibody, ZPR1 zinc finger L homeolog antibody, Zpr1 antibody, ZPR1 antibody, zpr1 antibody, zpr1.L antibody

Background: ZNF259 may be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. ZNF259 binds to the EGFR and is released from the receptor after activation.ZNF259 is essential for cell viability and its interaction with eEF-1alpha contributes to normal cellular proliferation.ZNF259 translocates from the cytoplasm to the nucleus after treatment of cells with mitogens. ZNF259 accumulates in the nucleolus of proliferating cells. Loss of ZNF259 caused disruption of nucleolar function, including preribosomal RNA expression. ZNF259 is an essential protein that is required for normal nucleolar function in proliferating cells.

Molecular Weight: 51 kDa

Gene ID: 8882

NCBI Accession: NP_003895

UniProt: O75312