CBLL1 antibody

Catalog No. ABIN2461939

This Rabbit Polyclonal antibody specifically detects CBLL1 in WB and ELISA. It exhibits reactivity toward Human, Mouse, Rat and Dog.

Quick Overview for CBLL1 antibody (ABIN2461939)

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBLL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CBLL1 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CBLL1.

Application Details

Application Notes: CBLL1 antibody can be used for detection of CBLL1 by ELISA at 1:62500. CBLL1 antibody can be used for detection of CBLL1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CBLL1 antibody at -20 °C.

Target Details for CBLL1

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Alternative Name: CBLL1

Background: Epithelial cell cadherin is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. CBLL1 is an E3 ubiquitin ligase that mediates ubiquitination of the CDH1 complex.Epithelial cell cadherin (CDH1, MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A, MIM 601623) that mediates ubiquitination of the CDH1 complex.

Molecular Weight: 55 kDa

Gene ID: 79872

NCBI Accession: NP_079090

UniProt: Q75N03