CBLL1 antibody (C-Term)

Catalog No. ABIN2781231

Cited in 1 publication. The Rabbit Polyclonal anti-CBLL1 antibody (ABIN2781231) specifically detects CBLL1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish (Danio rerio) and Pig samples.

Quick Overview for CBLL1 antibody (C-Term) (ABIN2781231)

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBLL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CBLL1 Antibody

Binding Specificity: C-Term

Purpose: CBLL1 Antibody - C-terminal region

Sequence: PFTQPGGMSP GIWPAPRGPP PPPRLQGPPS QTPLPGPHHP DQTRYRPYYQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CBLL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CBLL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096292

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CBLL1 antibody (ABIN2781231)

Horiuchi, Kawamura, Iwanari, Ohashi, Naito, Kodama, Hamakubo: "Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33292-302, (2013) (PubMed).

Target Details for CBLL1

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Alternative Name: CBLL1

Background:

Background Information: Epithelial cell cadherin is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. CBLL1 is an E3 ubiquitin ligase that mediates ubiquitination of the CDH1 complex.Epithelial cell cadherin (CDH1, MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A, MIM 601623) that mediates ubiquitination of the CDH1 complex.[supplied by OMIM].

Gene Name: Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1

Alternative Symbols: HAKAI, RNF188

Protein Name: E3 ubiquitin-protein ligase Hakai

Molecular Weight: 55kDa

Gene ID: 79872

NCBI Accession: NP_079090

UniProt: Q75N03