SLBP antibody

Catalog No. ABIN2462218

This Rabbit Polyclonal antibody specifically detects SLBP in WB and ELISA. It exhibits reactivity toward Human, Dog and Zebrafish (Danio rerio).

Quick Overview for SLBP antibody (ABIN2462218)

Target: SLBP (Stem-Loop Binding Protein (SLBP))

Reactivity: Human, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SLBP Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLBP.

Application Details

Application Notes: SLBP antibody can be used for detection of SLBP by ELISA at 1:312500. SLBP antibody can be used for detection of SLBP by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SLBP antibody at -20 °C.

Target Details for SLBP

Target: SLBP (Stem-Loop Binding Protein (SLBP))

Alternative Name: SLBP

Background: SLBP binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

Molecular Weight: 30 kDa

Gene ID: 7884

NCBI Accession: NP_006518

UniProt: Q14493