SLBP antibody (Middle Region)

Catalog No. ABIN2778993

The Rabbit Polyclonal anti-SLBP antibody (ABIN2778993) specifically detects SLBP in WB and IHC. The antibody is reactive with Human, Mouse, Cow, Dog, Zebrafish (Danio rerio), Rat, Guinea Pig and Horse samples.

Quick Overview for SLBP antibody (Middle Region) (ABIN2778993)

Target: SLBP (Stem-Loop Binding Protein (SLBP))

Reactivity: Human, Mouse, Cow, Dog, Zebrafish (Danio rerio), Rat, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SLBP Antibody

Binding Specificity: Middle Region

Purpose: SLBP Antibody - middle region

Sequence: INYGKNTIAY DRYIKEVPRH LRQPGIHPKT PNKFKKYSRR SWDQQIKLWK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SLBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLBP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112929

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLBP

Target: SLBP (Stem-Loop Binding Protein (SLBP))

Alternative Name: SLBP

Background:

Background Information: SLBP binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

Gene Name: Stem-loop binding protein

Alternative Symbols: HBP

Protein Name: Histone RNA hairpin-binding protein

Molecular Weight: 30kDa

Gene ID: 7884

NCBI Accession: NP_006518

UniProt: Q14493