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SLBP antibody (Middle Region)

SLBP Reactivity: Human, Mouse, Cow, Dog, Zebrafish (Danio rerio), Rat, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778993
  • Target See all SLBP Antibodies
    SLBP (Stem-Loop Binding Protein (SLBP))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Cow, Dog, Zebrafish (Danio rerio), Rat, Guinea Pig, Horse
    Host
    • 8
    • 2
    Rabbit
    Clonality
    • 8
    • 2
    Polyclonal
    Conjugate
    • 10
    This SLBP antibody is un-conjugated
    Application
    • 9
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    INYGKNTIAY DRYIKEVPRH LRQPGIHPKT PNKFKKYSRR SWDQQIKLWK
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SLBP. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SLBP
    Top Product
    Discover our top product SLBP Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 270 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SLBP (Stem-Loop Binding Protein (SLBP))
    Alternative Name
    SLBP (SLBP Products)
    Synonyms
    CG11886 antibody, Dmel\\CG11886 antibody, SLBP antibody, dSLBP antibody, dSLPB antibody, slbp antibody, cb157 antibody, sb:cb157 antibody, si:dkey-102m7.2 antibody, GB13630 antibody, HBP antibody, slbp1 antibody, xslbp antibody, stem-loop binding protein antibody, Stem-loop binding protein antibody, histone RNA hairpin-binding protein antibody, stem-loop binding protein L homeolog antibody, Slbp antibody, slbp antibody, SLBP antibody, LOC726745 antibody, EHI_178590 antibody, CpipJ_CPIJ008644 antibody, slbp.L antibody
    Background
    SLBP binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.
    Alias Symbols: HBP
    Protein Interaction Partner: UBC, CDK6, CDK4, UPF1, LSM10, ZNF473, USP8, ERI1,
    Protein Size: 270
    Molecular Weight
    30 kDa
    Gene ID
    7884
    NCBI Accession
    NM_006527, NP_006518
    UniProt
    Q14493
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