CDKN2AIP antibody

Catalog No. ABIN2462272

Product Details anti-CDKN2AIP Antibody

Target: CDKN2AIP (CDKN2A Interacting Protein (CDKN2AIP))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKN2AIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CARF.

Application Details

Application Notes: CARF antibody can be used for detection of CARF by ELISA at 1:312500. CARF antibody can be used for detection of CARF by western blot at 0.3125 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CARF antibody at -20 °C.

Target Details for CDKN2AIP

Target: CDKN2AIP (CDKN2A Interacting Protein (CDKN2AIP))

Alternative Name: CARF (CDKN2AIP Products)

Synonyms: CARF antibody, 4921511I16Rik antibody, AW208986 antibody, CDKN2AIP antibody, RGD1305302 antibody, CDKN2A interacting protein antibody, CDKN2A interacting protein L homeolog antibody, CDKN2AIP antibody, Cdkn2aip antibody, cdkn2aip antibody, cdkn2aip.L antibody

Background: CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.

Molecular Weight: 64 kDa

Gene ID: 55602

NCBI Accession: NP_060102

UniProt: Q9NXV6