ERI1 antibody

Catalog No. ABIN2462349

This anti-ERI1 antibody is a Rabbit Polyclonal antibody detecting ERI1 in WB and ELISA. Suitable for Human, Mouse, Rat and Dog.

Quick Overview for ERI1 antibody (ABIN2462349)

Target: ERI1 (Exoribonuclease 1 (ERI1))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ERI1 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human THEX1.

Application Details

Application Notes: THEX1 antibody can be used for detection of THEX1 by ELISA at 1:1562500. THEX1 antibody can be used for detection of THEX1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store THEX1 antibody at -20 °C.

Target Details for ERI1

Target: ERI1 (Exoribonuclease 1 (ERI1))

Alternative Name: THEX1

Background: THEX1 contains 1 SAP domain and 1 exonuclease domain. It is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi).

Molecular Weight: 38 kDa

Gene ID: 90459

NCBI Accession: NP_699163

UniProt: Q8IV48