Follistatin antibody
Quick Overview for Follistatin antibody (ABIN2462560)
Target
See all Follistatin (FST) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Purification
- Antibody is purified by protein A chromatography method.
-
Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FST.
-
-
-
-
Application Notes
- FST antibody can be used for detection of FST by ELISA at 1:312500. FST antibody can be used for detection of FST by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
-
Concentration
- 1 mg/mL
-
Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
-
Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
-
Storage
- 4 °C/-20 °C
-
Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store FST antibody at -20 °C.
-
-
- Follistatin (FST)
-
Alternative Name
- FST
-
Background
- Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release.Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
-
Molecular Weight
- 35 kDa, 38 kDa
-
Gene ID
- 10468
-
NCBI Accession
- NP_006341
-
UniProt
- Q6FHE1
-
Pathways
- Negative Regulation of Hormone Secretion
Target
-