UPB1 antibody

Catalog No. ABIN2462585

Product Details anti-UPB1 Antibody

Target: UPB1 (Ureidopropionase, beta (UPB1))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Drosophila melanogaster, Arabidopsis, C. elegans

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UPB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UPB1.

Application Details

Application Notes: UPB1 antibody can be used for detection of UPB1 by ELISA at 1:1562500. UPB1 antibody can be used for detection of UPB1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store UPB1 antibody at -20 °C.

Target Details for UPB1

Target: UPB1 (Ureidopropionase, beta (UPB1))

Alternative Name: UPB1 (UPB1 Products)

Synonyms: MGC82230 antibody, wu:fb69e03 antibody, zgc:64020 antibody, BUP1 antibody, AI195023 antibody, Bup1 antibody, ureidopropionase, beta S homeolog antibody, beta-ureidopropionase 1 antibody, ureidopropionase, beta antibody, UreidoPropionase Beta antibody, upb1.S antibody, UPB1 antibody, upb1 antibody, upb-1 antibody, Upb1 antibody

Background: UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activityThis gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.

Molecular Weight: 42 kDa

Gene ID: 51733

NCBI Accession: NP_057411

UniProt: Q9UBR1