NSMCE1 antibody

Catalog No. ABIN2462690

Product Details anti-NSMCE1 Antibody

Target: NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSMCE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NSMCE1.

Application Details

Application Notes: NSMCE1 antibody can be used for detection of NSMCE1 by ELISA at 1:1562500. NSMCE1 antibody can be used for detection of NSMCE1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NSMCE1 antibody at -20 °C.

Target Details for NSMCE1

Target: NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))

Alternative Name: NSMCE1 (NSMCE1 Products)

Synonyms: zgc:92777 antibody, NSMCE1 antibody, NSE1 antibody, 2510027N19Rik antibody, RGD1307760 antibody, NSE1 homolog, SMC5-SMC6 complex component antibody, NSE1 homolog, SMC5-SMC6 complex component L homeolog antibody, nsmce1 antibody, NSMCE1 antibody, nsmce1.L antibody, Nsmce1 antibody

Background: NSMCE1 is a probable component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.

Molecular Weight: 28 kDa

Gene ID: 197370

NCBI Accession: NP_659547

UniProt: Q8WV22

Pathways: Positive Regulation of Response to DNA Damage Stimulus