IRF6 antibody
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- Target See all IRF6 Antibodies
- IRF6 (Interferon Regulatory Factor 6 (IRF6))
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Reactivity
- Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRF6 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF6.
- Top Product
- Discover our top product IRF6 Primary Antibody
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- Application Notes
- IRF6 antibody can be used for detection of IRF6 by ELISA at 1:312500. IRF6 antibody can be used for detection of IRF6 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store IRF6 antibody at -20 °C.
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- Target
- IRF6 (Interferon Regulatory Factor 6 (IRF6))
- Alternative Name
- IRF6 (IRF6 Products)
- Synonyms
- IRF6 antibody, lps antibody, pit antibody, pps antibody, vws antibody, ofc6 antibody, xIRF-6 antibody, DKFZp469E012 antibody, LPS antibody, OFC6 antibody, PIT antibody, PPS antibody, PPS1 antibody, VWS antibody, VWS1 antibody, zgc:63500 antibody, AI876454 antibody, E230028I05Rik antibody, mirf6 antibody, interferon regulatory factor 6 antibody, interferon regulatory factor 6 S homeolog antibody, IRF6 antibody, irf6 antibody, irf6.S antibody, Irf6 antibody
- Background
- IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
- Molecular Weight
- 65 kDa, 69 kDa
- Gene ID
- 3664
- NCBI Accession
- NP_006138
- UniProt
- O14896
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