ABCD4
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ABCD4 antibody can be used for detection of ABCD4 by ELISA at 1:312500. ABCD4 antibody can be used for detection of ABCD4 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handling Advice
As with any antibody avoid repeat freeze-thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
For short periods of storage (days) store at 4 °C. For longer periods of storage, store ABCD4 antibody at -20 °C.
Target
ABCD4
(ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4))
ABC41 antibody, EST352188 antibody, MAHCJ antibody, P70R antibody, P79R antibody, PMP69 antibody, PXMP1L antibody, Pxmp1l antibody, ABCD4 antibody, zgc:153503 antibody, P69r antibody, ATP binding cassette subfamily D member 4 antibody, ATP-binding cassette, sub-family D (ALD), member 4 antibody, ABCD4 antibody, Abcd4 antibody, abcd4 antibody
Background
ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis.