NEU1 antibody

Catalog No. ABIN2462803

This Rabbit Polyclonal antibody specifically detects NEU1 in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NEU1 antibody (ABIN2462803)

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEU1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-NEU1 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NEU1.

Application Details

Application Notes: NEU1 antibody can be used for detection of NEU1 by ELISA at 1:312500. NEU1 antibody can be used for detection of NEU1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NEU1 antibody at -20 °C.

Target Details for NEU1

Target: NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))

Alternative Name: NEU1

Background: NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.

Molecular Weight: 40 kDa

Gene ID: 4758

NCBI Accession: NP_000425

UniProt: Q99519

Pathways: SARS-CoV-2 Protein Interactome