MTUS1 antibody

Catalog No. ABIN2462816

The Rabbit Polyclonal anti-MTUS1 antibody is suitable to detect MTUS1 in samples from Human, Mouse and Dog. It has been validated for WB and ELISA.

Quick Overview for MTUS1 antibody (ABIN2462816)

Target: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTUS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MTUS1 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MTUS1.

Application Details

Application Notes: MTUS1 antibody can be used for detection of MTUS1 by ELISA at 1:1562500. MTUS1 antibody can be used for detection of MTUS1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MTUS1 antibody at -20 °C.

Target Details for MTUS1

Target: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Alternative Name: MTUS1

Background: MTUS1 contains a C-terminal domain and is able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. One of the isoforms has been shown to be a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other isoforms may be nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.

Molecular Weight: 48 kDa, 141 kDa, 136 kDa, 59 kDa

Gene ID: 57509

NCBI Accession: NP_065800