Cadherin 7 antibody

Catalog No. ABIN2462981

Product Details anti-Cadherin 7 Antibody

Target: Cadherin 7 (CDH7)

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDH7.

Application Details

Application Notes: CDH7 antibody can be used for detection of CDH7 by ELISA at 1:12500. CDH7 antibody can be used for detection of CDH7 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDH7 antibody at -20 °C.

Target Details for Cadherin 7

Target: Cadherin 7 (CDH7)

Alternative Name: CDH7 (CDH7 Products)

Synonyms: CDH7L1 antibody, Cad7 antibody, 9330156F07Rik antibody, cadherin 7 antibody, cadherin 7, type 2 antibody, cadherin 7a antibody, CDH7 antibody, Cdh7 antibody, cdh7a antibody

Background: CDH7 is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures.This gene is a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures. Alternative splicing in the 5' UTR of this gene yields variant transcripts encoding the same protein.

Molecular Weight: 82 kDa, 88 kDa, 88 kDa, 89 kDa, 87 kDa

Gene ID: 1005

NCBI Accession: NP_004352

UniProt: Q9ULB5

Pathways: Cell-Cell Junction Organization