CDR2 antibody

Catalog No. ABIN2463409

This Rabbit Polyclonal antibody specifically detects CDR2 in ELISA, IHC and WB. It exhibits reactivity toward Human, Mouse, Rat and Dog.

Quick Overview for CDR2 antibody (ABIN2463409)

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-CDR2 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDR2.

Application Details

Application Notes: CDR2 antibody can be used for detection of CDR2 by ELISA at 1:312500. CDR2 antibody can be used for detection of CDR2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDR2 antibody at -20 °C.

Target Details for CDR2

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Alternative Name: CDR2

Background: Cdr2 normally sequesters c-Myc in the neuronal cytoplasm, thereby down-regulating c-Myc activity, and suggest a mechanism whereby inhibition of cdr2 function by autoantibodies in PCD may contribute to Purkinje neuronal.

Molecular Weight: 52 kDa

Gene ID: 1039

NCBI Accession: NP_001793

UniProt: Q01850