GABRD antibody

Catalog No. ABIN2463742

This Rabbit Polyclonal antibody specifically detects GABRD in WB and ELISA. It exhibits reactivity toward Human, Rat, Mouse and Dog.

Quick Overview for GABRD antibody (ABIN2463742)

Target: GABRD (GABA A Receptor delta (GABRD))

Reactivity: Human, Rat, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRD antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GABRD Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRD.

Application Details

Application Notes: GABRD antibody can be used for detection of GABRD by ELISA at 1:62500. GABRD antibody can be used for detection of GABRD by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GABRD antibody at -20 °C.

Target Details for GABRD

Target: GABRD (GABA A Receptor delta (GABRD))

Alternative Name: GABRD

Background: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. The GABRD gene encodes the delta subunit.Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit.

Molecular Weight: 51 kDa

Gene ID: 2563

NCBI Accession: NP_000806

UniProt: O14764