ABL2 antibody (truncated)

Catalog No. ABIN2464008

Product Details anti-ABL2 Antibody

Target: ABL2

Binding Specificity: truncated

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ABL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Immunogen: Ni-NTA purified truncated recombinant ABL2 expressed in E. Coli strain BL21 (DE3).

Clone: 1H1B11

Isotype: IgG1

Application Details

Application Notes: Dilution
Western Blot:1:200 - 1:1,000
IF:1:100 - 1:500
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: -20 °C

Storage Comment: ABL2 monoclonal antibody can be stored at -20 °C, stable for one year.

Target Details for ABL2

Target: ABL2

Alternative Name: ABL2 (ABL2 Products)

Synonyms: ABLL antibody, ARG antibody, Abll antibody, Arg antibody, AA536808 antibody, ABL proto-oncogene 2, non-receptor tyrosine kinase antibody, v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) antibody, ABL2 antibody, Abl2 antibody

Background: ABL2(ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization?c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.

Gene ID: 27

UniProt: P42684