CIB1 antibody (truncated)

Catalog No. ABIN2464036

This Mouse Monoclonal antibody specifically detects CIB1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for CIB1 antibody (truncated) (ABIN2464036)

Target: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CIB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 5A1F5E12-5A1H7E12

Product Details anti-CIB1 Antibody

Binding Specificity: truncated

Immunogen: Ni-NTA purified truncated recombinant CIB1 expressed in E. Coli strain BL21 (DE3).

Application Details

Application Notes: Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: -20 °C

Storage Comment: CIB1 monoclonal antibody can be stored at -20 °C, stable for one year.

Target Details for CIB1

Target: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Alternative Name: CIB1

Background: CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21 kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.

Gene ID: 10519

NCBI Accession: NP_001264693

UniProt: Q99828