CSNK1A1 antibody (truncated)

Catalog No. ABIN2464037

The Mouse Monoclonal anti-CSNK1A1 antibody is suitable to detect CSNK1A1 in samples from Human. It has been validated for WB, IHC and ELISA.

Quick Overview for CSNK1A1 antibody (truncated) (ABIN2464037)

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSNK1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 3C10F7-3C10G5-PMC01-4D12B3

Product Details anti-CSNK1A1 Antibody

Binding Specificity: truncated

Immunogen: Ni-NTA purified truncated recombinant CK1 expressed in E. Coli strain BL21 (DE3).

Isotype: IgG1

Application Details

Application Notes: Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: -20 °C

Storage Comment: CK1 monoclonal antibody can be stored at -20 °C, stable for one year.

Target Details for CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Alternative Name: CK1

Background: CK1 (also designated Cytokeratin 1 or KRT1 ),with 644-amino acid protein (about 70 kDa), is a member of the keratin family. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells.CK1 consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK1 is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.

Gene ID: 1452

UniProt: P48729

Pathways: WNT Signaling, Hedgehog Signaling