Desmin antibody (truncated)

Catalog No. ABIN2464045

This Mouse Monoclonal antibody specifically detects Desmin in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Desmin antibody (truncated) (ABIN2464045)

Target: Desmin (DES)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Desmin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 10H7D2

Product Details anti-Desmin Antibody

Binding Specificity: truncated

Immunogen: Ni-NTA purified truncated recombinant Desmin expressed in E. Coli strain BL21 (DE3).

Isotype: IgG1

Application Details

Application Notes: Western Blot:1:1,000 - 1:2,000
IHC(P):1:1,000 - 1:2,000
IHC(F):1:1,000 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS containing 0.03 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: -20 °C

Storage Comment: Desmin monoclonal antibody can be stored at -20 °C, stable for one year.

Target Details for Desmin

Target: Desmin (DES)

Alternative Name: Desmin

Background: Desmin (DES), with 470-amino acid protein (about 52 kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.

Gene ID: 1674

UniProt: P17661