GSTP1 antibody (truncated)

Catalog No. ABIN2464062

The Mouse Monoclonal anti-GSTP1 antibody (Clone 3F2C2) (ABIN2464062) specifically detects GSTP1 in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for GSTP1 antibody (truncated) (ABIN2464062)

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GSTP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 3F2C2

Product Details anti-GSTP1 Antibody

Binding Specificity: truncated

Immunogen: Ni-NTA purified truncated recombinant GSTP1 expressed in E. Coli strain BL21 (DE3).

Isotype: IgG1

Application Details

Application Notes: Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: -20 °C

Storage Comment: GSTP1 monoclonal antibody can be stored at -20 °C, stable for one year.

Target Details for GSTP1

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Alternative Name: GSTP1

Background: GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90 % ) of prostate carcinomas and is associated with transcriptional down-regulation.

Gene ID: 2950

UniProt: P09211

Pathways: Cellular Response to Molecule of Bacterial Origin