PTK6 antibody (truncated)

Catalog No. ABIN2464095

Product Details anti-PTK6 Antibody

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Binding Specificity: truncated

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTK6 antibody is un-conjugated

Application: ELISA

Immunogen: Ni-NTA purified truncated recombinant PTK6 expressed in E. Coli strain BL21 (DE3).

Clone: 2H12B8

Isotype: IgG2b

Application Details

Application Notes: ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: -20 °C

Storage Comment: PTK6 monoclonal antibody can be stored at -20 °C, stable for one year.

Target Details for PTK6

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Alternative Name: PTK6 (PTK6 Products)

Synonyms: BRK antibody, Sik antibody, Tksk antibody, tks antibody, zgc:153964 antibody, protein tyrosine kinase 6 antibody, PTK6 protein tyrosine kinase 6 antibody, PTK6 protein tyrosine kinase 6b antibody, PTK6 antibody, Ptk6 antibody, ptk6b antibody

Background: PTK6 (protein tyrosine kinase 6, BRK or FLJ42088),with 451-amino acid protein (about 51 kDa), encods a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphory-lation. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. And Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes, but not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype.

Gene ID: 5753

UniProt: Q13882