SNCG antibody (truncated)
Quick Overview for SNCG antibody (truncated) (ABIN2464104)
Target
See all SNCG AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- truncated
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Purification
- Antibody is purified by protein A affinity chromatography.
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Immunogen
- Ni-NTA purified truncated recombinant SNCG expressed in E. Coli strain BL21 (DE3).
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Isotype
- IgG1
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Application Notes
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Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
Restrictions
- For Research Use only
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Buffer
- Purified antibody in PBS containing 0.03 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Storage
- -20 °C
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Storage Comment
- SNCG (breast cancer-specific protein 1) monoclonal antibody can be stored at -20 °C, stable for one year.
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- SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))
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Alternative Name
- SNCG
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Background
- SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
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Gene ID
- 6623
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UniProt
- O76070
Target
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