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LDLR antibody (AA 29-205)

This anti-LDLR antibody is a Chicken Polyclonal antibody detecting LDLR in WB. Suitable for Human, Mouse and Rat.
Catalog No. ABIN2467854

Quick Overview for LDLR antibody (AA 29-205) (ABIN2467854)

Target

See all LDLR Antibodies
LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivity

  • 89
  • 42
  • 28
  • 17
  • 16
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Mouse, Rat

Host

  • 81
  • 15
  • 4
Chicken

Clonality

  • 76
  • 23
  • 1
Polyclonal

Conjugate

  • 59
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LDLR antibody is un-conjugated

Application

  • 70
  • 41
  • 30
  • 29
  • 16
  • 14
  • 13
  • 11
  • 8
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 16
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-205

    Purification

    Antigen affinity-purified
  • Application Notes

    LDL-R antibody can be used for the detection of LDL-R by Western blot, may also work for IHC and ICC.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Phosphate-Buffered Saline. No preservatives added.

    Preservative

    Without preservative

    Handling Advice

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    Storage

    4 °C/-20 °C

    Storage Comment

    LDLR antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
  • Target

    LDLR (Low Density Lipoprotein Receptor (LDLR))

    Alternative Name

    LDLR

    Background

    Low density lipoprotein receptor. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia.

    Molecular Weight

    95.4 kDa (calculated)

    Gene ID

    3949

    NCBI Accession

    NP_000518

    UniProt

    P01130

    Pathways

    Hepatitis C, Lipid Metabolism
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