EPH Receptor A4 antibody (C-Term)

Catalog No. ABIN2469317

The Rabbit Polyclonal anti-EPH Receptor A4 antibody has been validated for ELISA and IHC. It is suitable to detect EPH Receptor A4 in samples from Human, Mouse, Rat, Cow, Dog, Monkey, Rabbit, Horse, Pig, Bat, Hamster, Gibbon and Gorilla.

Quick Overview for EPH Receptor A4 antibody (C-Term) (ABIN2469317)

Target: EPH Receptor A4 (EPHA4)

Reactivity: Human, Mouse, Rat, Cow, Dog, Monkey, Rabbit, Horse, Pig, Bat, Hamster, Gibbon, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-EPH Receptor A4 Antibody

Binding Specificity: C-Term

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: EPHA4 antibody was raised against a peptide located in the C-Terminal domain of EPHA4 (Human).

Application Details

Application Notes: EPHA4 antibody can be used in immunohistochemistry starting at 7.3 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: EPHA4 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for EPH Receptor A4

Target: EPH Receptor A4 (EPHA4)

Alternative Name: EPHA4

Background: Nak1, a NR4 Nerve Growth Factor-Like receptor, has been shown to affect the hypothalamic-pituitary axis, neuronal differentiation, neuroendocrine regulation of adrenocortical function, and T-cell apoptosis. Nak1 also is known as nuclear receptor Tr3 and is similar to mouse Nur77 and rat NGFI-B. It is encoded by one of the immediate early genes (IEG) in response to nerve growth factor and other serum growth factors. Nak1 can bind to DNA as a monomer, homodimer, or heterodimer (with retinoid X receptors). Nak1 has been shown to inhibit vascular lesion formation and could serve as a novel target in the treatment of vascular diseases.

Gene ID: 2043

UniProt: P54764

Pathways: RTK Signaling