CCR8 antibody (3rd Cytoplasmic Domain)

Catalog No. ABIN2469366

The Rabbit Polyclonal anti-CCR8 antibody (ABIN2469366) specifically detects CCR8 in ELISA and IHC. The antibody is reactive with Human and Gorilla samples.

Quick Overview for CCR8 antibody (3rd Cytoplasmic Domain) (ABIN2469366)

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reactivity: Human, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR8 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-CCR8 Antibody

Binding Specificity: 3rd Cytoplasmic Domain

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: CCR8 antibody was raised against a peptide located in the 3rd cytoplasmic domain of CCR8 (Human).

Application Details

Application Notes: CCR8 antibody can be used in immunohistochemistry starting at 4.8 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: CR8 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Alternative Name: CCR8

Background: CCR8, a Chemokine Receptor, binds the CC-chemokine I-309, which is secreted by umbilical vein endothelial cells. CCR8 also binds viral monocyte inflammatory protein-I (vMIP-I), which is induced by Kaposi sarcoma-related human herpesvirus-8. CCR8 induces endothelial chemotaxis and may function as an HIV-1 co-receptor on primary human cells, contributing to HIV-1-induced thymic pathogenesis (Lee et al., 2000).

Gene ID: 1237

UniProt: P51685