HTR7 antibody (3rd Cytoplasmic Domain)

Catalog No. ABIN2469430

This Rabbit Polyclonal antibody specifically detects HTR7 in ELISA and IHC. It exhibits reactivity toward Human, Gibbon and Gorilla.

Quick Overview for HTR7 antibody (3rd Cytoplasmic Domain) (ABIN2469430)

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Reactivity: Human, Gibbon, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-HTR7 Antibody

Binding Specificity: 3rd Cytoplasmic Domain

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: HTR7 antibody was raised against a peptide located in the 3rd cytoplasmic domain of HTR7 (Human).

Application Details

Application Notes: HTR7 antibody can be used in immunohistochemistry starting at 6 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: HTR7 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for HTR7

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Alternative Name: HTR7

Background: 5-HT7 Receptor is a Serotonin Receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. This receptor has been implicated in depression, autistism, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa, isoform b: 432aa, isoform d: 479aa.

Gene ID: 3363

UniProt: P34969

Pathways: JAK-STAT Signaling