HTR7 antibody (N-Term)

Catalog No. ABIN2469437

The Rabbit Polyclonal anti-HTR7 antibody has been validated for IHC. It is suitable to detect HTR7 in samples from Human, Dog and Monkey.

Quick Overview for HTR7 antibody (N-Term) (ABIN2469437)

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Reactivity: Human, Dog, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR7 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-HTR7 Antibody

Binding Specificity: N-Term

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except LTBR (50 % ).

Purification: Immunoaffinity Chromatography

Immunogen: HTR7 antibody was raised against a peptide located in the N-Terminal domain of HTR7 (Human).

Application Details

Application Notes: HTR7 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200 - 1:300.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: HTR7 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for HTR7

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Alternative Name: HTR7

Background: 5-HT7 Receptor is a Serotonin Receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract. This receptor has been implicated in depression, autistism, and other neuropsychiatric disorders. Three protein isoforms have been documented: isoform a: 445aa, isoform b: 432aa, isoform d: 479aa.

Gene ID: 3363

UniProt: P34969

Pathways: JAK-STAT Signaling