ADRA1B antibody (3rd Cytoplasmic Domain)

Catalog No. ABIN2469448

This Rabbit Polyclonal antibody specifically detects ADRA1B in ELISA and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Pig, Monkey, Hamster, Horse, Gibbon and Gorilla.

Quick Overview for ADRA1B antibody (3rd Cytoplasmic Domain) (ABIN2469448)

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Monkey, Hamster, Horse, Gibbon, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRA1B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-ADRA1B Antibody

Binding Specificity: 3rd Cytoplasmic Domain

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: ADRA1B antibody was raised against a peptide located in the 3rd cytoplasmic domain of ADRA1B (Human).

Application Details

Application Notes: ADRA1B antibody can be used in immunohistochemistry starting at 15 - 20 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: ADRA1B antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for ADRA1B

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Alternative Name: ADRA1B

Background: The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation.

Gene ID: 147

UniProt: P35368

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process