PDE8A antibody (N-Term)

Catalog No. ABIN2469454

This Rabbit Polyclonal antibody specifically detects PDE8A in IHC. It exhibits reactivity toward Human, Rabbit, Dog, Horse, Pig, Gibbon and Gorilla.

Quick Overview for PDE8A antibody (N-Term) (ABIN2469454)

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Reactivity: Human, Rabbit, Dog, Horse, Pig, Gibbon, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE8A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-PDE8A Antibody

Binding Specificity: N-Term

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: PDE8A antibody was raised against a peptide located in the near N-Terminus of PDE8A (Human).

Application Details

Application Notes: PDE8A antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200 - 1:300.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: PDE8A antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for PDE8A

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Alternative Name: PDE8A

Background: Phosphodiesterase 8A, a high affinity, cAMP-specific phosphodiesterase, has been implicated in penile erectile dysfunction. PDE8A activity is inhibited by dipyridamole, but not by rolipram, zaprinast, or IBMX. At least five splice variants and four protein isoforms have been reported.

Gene ID: 5151

UniProt: O60658

Pathways: cAMP Metabolic Process