PDE8B antibody (Internal Region)
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- Target See all PDE8B Antibodies
- PDE8B (phosphodiesterase 8B (PDE8B))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Monkey, Gibbon, Gorilla
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PDE8B antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Specificity
- BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Purification
- Immunoaffinity Chromatography
- Immunogen
- PDE8B antibody was raised against a peptide located near the internal domain of PDE8B (Human).
- Top Product
- Discover our top product PDE8B Primary Antibody
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- Application Notes
- PDE8B antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, 0.1 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies avoid freeze/thaw cycles.
- Storage
- 4 °C/-80 °C
- Storage Comment
- PDE8B antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
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- Target
- PDE8B (phosphodiesterase 8B (PDE8B))
- Alternative Name
- PDE8B (PDE8B Products)
- Synonyms
- PDE8B antibody, ADSD antibody, PPNAD3 antibody, B230331L10Rik antibody, C030047E14Rik antibody, RNPDE8B antibody, phosphodiesterase 8B antibody, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B antibody, PDE8B antibody, LOC100468338 antibody, pde8b antibody, Pde8b antibody
- Background
- Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX.
- Gene ID
- 8622
- UniProt
- O95263
- Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
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