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PDE9A antibody (Internal Region)

PDE9A Reactivity: Human, Dog, Monkey, Gibbon IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2469457
  • Target See all PDE9A Antibodies
    PDE9A (phosphodiesterase 9A (PDE9A))
    Binding Specificity
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 23
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Dog, Monkey, Gibbon
    Host
    • 19
    • 4
    Rabbit
    Clonality
    • 21
    • 2
    Polyclonal
    Conjugate
    • 17
    • 3
    • 2
    • 1
    This PDE9A antibody is un-conjugated
    Application
    • 17
    • 11
    • 11
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    Immunohistochemistry (IHC)
    Specificity
    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Purification
    Immunoaffinity Chromatography
    Immunogen
    PDE9A antibody was raised against a peptide located near the internal domain of PDE9A (Human).
    Top Product
    Discover our top product PDE9A Primary Antibody
  • Application Notes
    PDE9A antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, 0.1 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies avoid freeze/thaw cycles.
    Storage
    4 °C/-80 °C
    Storage Comment
    PDE9A antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
  • Target
    PDE9A (phosphodiesterase 9A (PDE9A))
    Alternative Name
    PDE9A (PDE9A Products)
    Synonyms
    PDE9A antibody, MGC116558 antibody, Pde9a antibody, HSPDE9A2 antibody, PDE9A1 antibody, phosphodiesterase 9A antibody, phosphodiesterase 9A S homeolog antibody, high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A antibody, PDE9A antibody, pde9a.S antibody, Pde9a antibody, LOC100549810 antibody, pde9a antibody
    Background
    Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.
    Gene ID
    5152
    UniProt
    O76083
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