PDE1C antibody (C-Term)
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- Target See all PDE1C Antibodies
- PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Monkey, Bat, Hamster, Gorilla, Orang-Utan, Gibbon
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PDE1C antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Specificity
- BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Purification
- Immunoaffinity Chromatography
- Immunogen
- PDE1C antibody was raised against a peptide located in the C-Terminal domain of PDE1C (Human).
- Top Product
- Discover our top product PDE1C Primary Antibody
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- Application Notes
- PDE1C antibody can be used in immunohistochemistry starting at 10 μg/mL, and flow cytometry.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, 0.1 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- As with all antibodies avoid freeze/thaw cycles.
- Storage
- 4 °C/-80 °C
- Storage Comment
- PDE1C antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
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- Target
- PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
- Alternative Name
- PDE1C (PDE1C Products)
- Synonyms
- CG14940 antibody, CG14942 antibody, CG14943 antibody, CG14944 antibody, CG31757 antibody, CG31758 antibody, CG42325 antibody, CG44007 antibody, Dmel\\CG44007 antibody, Dmel_CG14940 antibody, Dmel_CG14943 antibody, Dmel_CG14944 antibody, Dmel_CG31757 antibody, Dmel_CG31758 antibody, Dmel_CG42325 antibody, PDE1C antibody, PDE1c antibody, GB13690 antibody, Hcam3 antibody, Phosphodiesterase 1c antibody, phosphodiesterase 1C antibody, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A antibody, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C antibody, phosphodiesterase 1C, calmodulin-dependent b antibody, Pde1c antibody, PDE1C antibody, LOC724389 antibody, LOC100019026 antibody, pde1cb antibody
- Background
- Phosphodiesterase 1C is a cAMP/cGMP dual-specific, calcium/calmodullin-dependent phosphodiesterase. PDE1C has been shown to affect vascular smooth muscle proliferation and atherosclerosis, insulin secretion regulation, spermatozoa development, and erectile dysfunction. At least five PDE1C isoforms have been reported, the expression of which are regulated in a tissue/cell-specific manner.
- Gene ID
- 5137
- UniProt
- Q14123
- Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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