CX3CR1 antibody (3rd Extracellular Domain)

Catalog No. ABIN2469503

Product Details anti-CX3CR1 Antibody

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Binding Specificity: 3rd Extracellular Domain

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: CX3CR1 antibody was raised against a peptide located in the 3rd extracellular domain of CX3CR1 (Human).

Application Details

Application Notes: CX3CR1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: CX3CR1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CX3CR1 (CX3CR1 Products)

Synonyms: CCRL1 antibody, CMKBRL1 antibody, CMKDR1 antibody, GPR13 antibody, GPRV28 antibody, V28 antibody, Rbs11 antibody, C-X3-C motif chemokine receptor 1 antibody, chemokine (C-X3-C motif) receptor 1 antibody, CX3C chemokine receptor 1 antibody, CX3CR1 antibody, Cx3cr1 antibody, LOC100559882 antibody

Background: CX3CR1 a Chemokine Receptor is an HIV coreceptor, as well as a leukocyte chemotactic/adhesion receptor for fractalkine, also known as neurotactin. CX3CR1 mediates chemotactic responses to the soluble form of fractalkine in neutrophils and T cells, and cytoadhesion to cells expressing membrane-anchored fractalkine, such as monocytes, T cells, and neutrophils. Cells transfected with CX3CR1 exhibited chemotaxis and transient increases in intracellular calcium concentration when exposed to fractalkine.

Gene ID: 1524

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin