The Rabbit Polyclonal anti-Prostaglandin E Synthase antibody (ABIN2469510) specifically detects Prostaglandin E Synthase in IHC.
The antibody is reactive with Human, Rat, Rabbit, Monkey, Pig, Chicken, Cow, Dog, Horse, Zebrafish (Danio rerio), Gibbon and Gorilla samples.
PTGES antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200 - 1:400.
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
As with all antibodies avoid freeze/thaw cycles.
Storage
4 °C/-80 °C
Storage Comment
PTGES antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Target
Prostaglandin E Synthase (PTGES)
Alternative Name
PTGES
Background
PGES-1 is a membrane associated protein involved in eicosanoid and glutathione metabolism as part of the arachidonic acid signaling pathway. The expression of this protein is induced by the proinflammatory cytokine IL-1B and its activity is glutathione dependent. PGES is also expressed at high levels in P53 expressing cells.