ITGA2 antibody (Extracellular Domain)

Catalog No. ABIN2469539

The Rabbit Polyclonal anti-ITGA2 antibody is suitable to detect ITGA2 in samples from Human, Monkey, Dog, Pig, Gibbon and Gorilla. It has been validated for IHC.

Quick Overview for ITGA2 antibody (Extracellular Domain) (ABIN2469539)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivity: Human, Monkey, Dog, Pig, Gibbon, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-ITGA2 Antibody

Binding Specificity: Extracellular Domain

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: Integrin alpha 2 antibody was raised against a peptide located near the Extracellular domain of Integrin alpha 2 (Human).

Application Details

Application Notes: Integrin alpha 2 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200 - 1:400.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: Integrin alpha 2 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: Integrin alpha 2

Background: ITGA2 encodes integrin alpha chain 2. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing alpha integrin 2 combines with beta integrin 1 to form a collagen-binding integrin referred to as glycoprotein Ia/IIa when expressed on platelets, and very late (activation) antigen 2 ('VLA-2') when found on T-cells. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Gene ID: 3673

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex