PLA2G3 antibody (Internal Region)

Catalog No. ABIN2469549

Product Details anti-PLA2G3 Antibody

Target: PLA2G3 (Phospholipase A2, Group III (PLA2G3))

Binding Specificity: Internal Region

Reactivity: Human, Cow, Monkey, Pig, Gorilla, Gibbon

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: PLA2G3 antibody was raised against a peptide located near the internal domain of PLA2G3 (Human).

Application Details

Application Notes: PLA2G3 antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: PLA2G3 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for PLA2G3

Target: PLA2G3 (Phospholipase A2, Group III (PLA2G3))

Alternative Name: PLA2G3 (PLA2G3 Products)

Synonyms: PLA2G3 antibody, GIII-SPLA2 antibody, SPLA2III antibody, 9130003P18Rik antibody, phospholipase A2 group III antibody, phospholipase A2, group III antibody, PLA2G3 antibody, Pla2g3 antibody

Background: Human group III secreted phospholipase A2 belongs to a superfamily of intracellular and secreted enzymes that catalyze the hydrolysis of glycerophospholipids at the sn-2 position to release fatty acids and lysophospholipids. Group III PLA2 enzymes were originally identified in invertebrates such as bees and scorpions. Human group III sPLA2 has been shown to be a calcium dependent enzyme. It consists of a central group III sPLA2 domain flanked by unique N- and C-terminal domains that are proteolytically removed in most tissues. The sPLA2 domain is sufficient for catalytic activity. SPLA2-III is preferentially expressed in the microvascular endothelium of tissues with inflammation, ischemic injury and cancer.

Gene ID: 50487

UniProt: Q9NZ20