The Rabbit Polyclonal anti-EGR1 antibody (ABIN2470185) specifically detects EGR1 in WB, ELISA and IHC.
The antibody is reactive with Human, Mouse and Chimpanzee samples.
EGR1
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Early Growth Response 1 antibody can be used in ELISA, Western Blot starting at 2 - 4 μg/mL, immunohistochemistry starting at 5 μg/mL, and immunofluorescence.
Restrictions
For Research Use only
Format
Liquid
Buffer
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
As with all antibodies avoid freeze/thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
Store Early Growth Response 1 antibody at 4 °C or -20 °C.
Target
EGR1
(Early Growth Response 1 (EGR1))
Alternative Name
Early Growth Response 1
Background
EGR-1 (also called Early Growth Response protein 1, Krox-24 protein, ZIF268, Nerve growth factor-induced protein A or NGFI-A, Transcription factor ETR103, and Zinc finger protein 225 or AT225) is a transcriptional regulator that recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3' (EGR-site). EGR-1 activates the transcription of target genes whose products are required for mitogenesis and differentiation. EGR-1 is a nuclear protein induced by growth factors. Expression has been identified in a variety of cancers.