CD79b antibody

Catalog No. ABIN2472460

The Rat Monoclonal anti-CD79b antibody has been validated for FACS, WB, IP and ELISA. It is suitable to detect CD79b in samples from Human, Mouse, Rat, Dog, Pig, Koala and Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius). There are 3+ publications available.

Quick Overview for CD79b antibody (ABIN2472460)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivity: Human, Mouse, Rat, Dog, Pig, Koala, Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)

Host: Rat

Clonality: Monoclonal

Conjugate: This CD79b antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), ELISA

Clone: AT107-2

Product Details anti-CD79b Antibody

Cross-Reactivity: Cat (Feline), Dog (Canine), Human, Koala (Phascolarctos cinereus), Pig (Porcine), Rat (Rattus), Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)

Characteristics: Purified IgG

Purification: Purified

Immunogen: Peptide containing 20 amino acid residues from mouse CD79b conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-CD79b antibody (ABIN2472460)

Vendel, Calemine-Fenaux, Izrael-Tomasevic, Chauhan, Arnott, Eaton: "B and T lymphocyte attenuator regulates B cell receptor signaling by targeting Syk and BLNK." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1509-17, (2009) (PubMed).

Dornan, Bennett, Chen, Dennis, Eaton, Elkins, French, Go, Jack, Junutula, Koeppen, Lau, McBride, Rawstron, Shi, Yu, Yu, Yue, Zheng, Ebens, Polson: "Therapeutic potential of an anti-CD79b antibody-drug conjugate, anti-CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma." in: Blood, Vol. 114, Issue 13, pp. 2721-9, (2009) (PubMed).

Piriou-Guzylack, Salmon: "Membrane markers of the immune cells in swine: an update." in: Veterinary research, Vol. 39, Issue 6, pp. 54, (2008) (PubMed).

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79b

Background: Synonyms: B29

Gene ID: 15985

UniProt: P15530

Pathways: BCR Signaling