CD79b antibody

Catalog No. ABIN2472460

Product Details anti-CD79b Antibody

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivity: Human, Mouse, Rat, Dog, Pig, Koala, Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)

Host: Rat

Clonality: Monoclonal

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), ELISA

Cross-Reactivity: Cat (Feline), Dog (Canine), Human, Koala (Phascolarctos cinereus), Pig (Porcine), Rat (Rattus), Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)

Characteristics: Purified IgG

Purification: Purified

Immunogen: Peptide containing 20 amino acid residues from mouse CD79b conjugated to Keyhole Limpet Hemocyanin (KLH).

Clone: AT107-2

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-CD79b antibody (ABIN2472460)

Vendel, Calemine-Fenaux, Izrael-Tomasevic, Chauhan, Arnott, Eaton: "B and T lymphocyte attenuator regulates B cell receptor signaling by targeting Syk and BLNK." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1509-17, (2009) (PubMed).

Dornan, Bennett, Chen, Dennis, Eaton, Elkins, French, Go, Jack, Junutula, Koeppen, Lau, McBride, Rawstron, Shi, Yu, Yu, Yue, Zheng, Ebens, Polson: "Therapeutic potential of an anti-CD79b antibody-drug conjugate, anti-CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma." in: Blood, Vol. 114, Issue 13, pp. 2721-9, (2009) (PubMed).

Piriou-Guzylack, Salmon: "Membrane markers of the immune cells in swine: an update." in: Veterinary research, Vol. 39, Issue 6, pp. 54, (2008) (PubMed).

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79b

Background: Synonyms: B29

Gene ID: 15985

UniProt: P15530

Pathways: BCR Signaling