Connexin 43/GJA1 antibody (pSer368)

Catalog No. ABIN2473077

This anti-Connexin 43/GJA1 antibody is a Rabbit Polyclonal antibody detecting Connexin 43/GJA1 in WB. Suitable for Human, Rat, Mouse, Dog, Cow, Chicken, Guinea Pig and Zebrafish (Danio rerio). This Primary Antibody has been cited in 2+ publications.

Quick Overview for Connexin 43/GJA1 antibody (pSer368) (ABIN2473077)

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Chicken, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Connexin 43/GJA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Connexin 43/GJA1 Antibody

Binding Specificity: pSer368

Cross-Reactivity: Chicken, Cow (Bovine), Dog (Canine), Guinea Pig, Human, Mouse (Murine), Zebrafish

Characteristics: Purified IgG

Purification: Purified

Immunogen: Synthetic phosphopeptide corresponding to an amino acid sequence within connexin43 which includes phosphorylated Ser368

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

References for anti-Connexin 43/GJA1 antibody (ABIN2473077)

Bao, Altenberg, Reuss: "Mechanism of regulation of the gap junction protein connexin 43 by protein kinase C-mediated phosphorylation." in: American journal of physiology. Cell physiology, Vol. 286, Issue 3, pp. C647-54, (2004) (PubMed).

Bao, Reuss, Altenberg: "Regulation of purified and reconstituted connexin 43 hemichannels by protein kinase C-mediated phosphorylation of Serine 368." in: The Journal of biological chemistry, Vol. 279, Issue 19, pp. 20058-66, (2004) (PubMed).

Target Details for Connexin 43/GJA1

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Alternative Name: CONNEXIN 43

Background: Synonyms: GAP JUNCTION ALPHA-1 PROTEIN

Gene ID: 24392

UniProt: P08050

Pathways: MAPK Signaling, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization