PRKDC antibody

Catalog No. ABIN2473350

This anti-PRKDC antibody is a Rabbit Polyclonal antibody detecting PRKDC in WB, IP, IHC (p) and GS. Suitable for Human, Mouse, Rat and Hamster. This Primary Antibody has been cited in 2+ publications.

Quick Overview for PRKDC antibody (ABIN2473350)

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Reactivity: Human, Mouse, Rat, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKDC antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Gel Shift (GS)

Product Details anti-PRKDC Antibody

Cross-Reactivity: Hamster, Mouse (Murine), Rat (Rattus)

Characteristics: Serum

Immunogen: Human DNA-PKcs fragment

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

References for anti-PRKDC antibody (ABIN2473350)

Hoek, Myers, Stillman: "An analysis of CAF-1-interacting proteins reveals dynamic and direct interactions with the KU complex and 14-3-3 proteins." in: The Journal of biological chemistry, Vol. 286, Issue 12, pp. 10876-87, (2011) (PubMed).

Jayaram, Gilson, Ehrlich, Yu, Ketner, Hanakahi: "E1B 55k-independent dissociation of the DNA ligase IV/XRCC4 complex by E4 34k during adenovirus infection." in: Virology, Vol. 382, Issue 2, pp. 163-70, (2008) (PubMed).

Target Details for PRKDC

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Alternative Name: DNA PKcs

Gene ID: 5591

UniProt: P78527

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response