CDKN1A antibody (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1))

Details for Product anti-CDKN1A Antibody No. ABIN2475991
Antigen
  • p21
  • cip1
  • p16Xic2
  • CCND1
  • sdi1
  • waf1
  • cap20
  • cdkn1
  • mda-6
  • p21cip1
  • CDKN1A
  • si:ch1073-48m5.2
  • Cip1
  • UV96
  • Waf1
  • CAP20
  • CDKN1
  • CIP1
  • MDA-6
  • P21
  • SDI1
  • WAF1
  • p21CIP1
  • CDKI
  • Cdkn1
  • mda6
  • p21Cip1
  • p21WAF
  • cyclin-dependent kinase inhibitor 1A L homeolog
  • cyclin-dependent kinase inhibitor 1
  • cyclin D1
  • cyclin-dependent kinase inhibitor 1A
  • cyclin dependent kinase inhibitor 1A
  • cyclin-dependent kinase inhibitor 1A (P21)
  • cdkn1a.L
  • cki1
  • CCND1
  • cdkn1a
  • CDKN1A
  • Cdkn1a
Reactivity
Human
502
190
132
57
49
7
6
5
4
1
1
1
1
1
1
1
Host
Mouse
340
205
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CDKN1A antibody is un-conjugated
31
27
22
20
20
20
9
9
9
9
9
9
5
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
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4
Application
Immunoprecipitation (IP), Western Blotting (WB)
281
177
171
167
147
105
68
66
53
29
18
17
9
6
6
2
2
1
Options
Immunogen Human p21 protein
Clone WA-1
Isotype IgG1
Specificity This antibody recognises the human cyclin-dependent kinase inhibitor p21/WAF1, which is an important cell cycle regulatory protein, also known as CIP1.The p21 protein inhibits cell cycle progression at both the G1 and G2 checkpoints. The expression of p21 is inducible by a wide range of stress stimuli.This antibody detects a band of approximately 21kD in MCF-7 cell lysates following UV radiation.
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others CDKN1A products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name p21/WAF1 (CDKN1A Antibody Abstract)
Gene ID 1026
UniProt P38936
Pathways p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Supplier Images
Image no. 1 for anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) antibody (ABIN2475991) anti-Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) antibody
Product cited in: Kotala, Uldrijan, Horky, Trbusek, Strnad, Vojtesek: "Potent induction of wild-type p53-dependent transcription in tumour cells by a synthetic inhibitor of cyclin-dependent kinases." in: Cellular and molecular life sciences : CMLS, Vol. 58, Issue 9, pp. 1333-9, 2001 (PubMed).

Kolár, Murray, Scott, Harrison, Vojt?sek, Dusek: "Relation of Bcl-2 expression to androgen receptor, p21WAF1/CIP1, and cyclin D1 status in prostate cancer." in: Molecular pathology : MP, Vol. 53, Issue 1, pp. 15-8, 2000 (PubMed).

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