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CDKN1A antibody (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1)) Primary Antibody

CDKN1A Reactivity: Human IP, WB Host: Mouse Monoclonal WA-1 unconjugated
Pubmed (2)
Catalog No. ABIN2475991
$300.24
Plus shipping costs $45.00
0.1 mg
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  • Target
    CDKN1A
    Reactivity
    Human
    • 291
    • 122
    • 83
    • 26
    • 23
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Host
    Mouse
    • 222
    • 93
    • 1
    Clonality
    Monoclonal
    Conjugate
    This CDKN1A antibody is un-conjugated
    • 109
    • 24
    • 22
    • 18
    • 16
    • 14
    • 14
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Application
    Immunoprecipitation (IP), Western Blotting (WB)
    • 157
    • 111
    • 97
    • 81
    • 76
    • 59
    • 53
    • 43
    • 38
    • 21
    • 15
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    Specificity
    This antibody recognises the human cyclin-dependent kinase inhibitor p21/WAF1, which is an important cell cycle regulatory protein, also known as CIP1.The p21 protein inhibits cell cycle progression at both the G1 and G2 checkpoints. The expression of p21 is inducible by a wide range of stress stimuli.This antibody detects a band of approximately 21kD in MCF-7 cell lysates following UV radiation.
    Characteristics
    Purified IgG
    Purification
    Purified
    Immunogen
    Human p21 protein
    Clone
    WA-1
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
  • Kotala, Uldrijan, Horky, Trbusek, Strnad, Vojtesek: "Potent induction of wild-type p53-dependent transcription in tumour cells by a synthetic inhibitor of cyclin-dependent kinases." in: Cellular and molecular life sciences : CMLS, Vol. 58, Issue 9, pp. 1333-9, 2001 (PubMed).

    Kolár, Murray, Scott, Harrison, Vojt?sek, Dusek: "Relation of Bcl-2 expression to androgen receptor, p21WAF1/CIP1, and cyclin D1 status in prostate cancer." in: Molecular pathology : MP, Vol. 53, Issue 1, pp. 15-8, 2000 (PubMed).

  • Target
    CDKN1A
    Alternative Name
    p21/WAF1 (CDKN1A Antibody Abstract)
    Synonyms
    CCND1, CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, CDKI, Cdkn1, Waf1, mda6, p21Cip1, p21WAF, Cip1, UV96, p21, cip1, p16Xic2, sdi1, waf1, cap20, cdkn1, mda-6, p21cip1, si:ch1073-48m5.2, KRAS2, p21ras, cyclin D1, cyclin dependent kinase inhibitor 1A, cyclin-dependent kinase inhibitor 1A (P21), cyclin-dependent kinase inhibitor 1A, cyclin-dependent kinase inhibitor 1A L homeolog, cyclin-dependent kinase inhibitor 1, KRAS proto-oncogene, GTPase, CCND1, CDKN1A, Cdkn1a, cdkn1a.L, cki1, cdkn1a, KRAS
    Gene ID
    1026
    UniProt
    P38936
    Pathways
    p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy
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