PIK3R2 antibody (Subunit beta)

Catalog No. ABIN2476135

This Mouse Monoclonal antibody specifically detects PIK3R2 in WB, IP and IHC (fro). It exhibits reactivity toward Human, Cow and Monkey and has been mentioned in 3+ publications.

Quick Overview for PIK3R2 antibody (Subunit beta) (ABIN2476135)

Target: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Reactivity: Human, Cow, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This PIK3R2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: T15

Product Details anti-PIK3R2 Antibody

Binding Specificity: Subunit beta

Cross-Reactivity: Human, Monkey

Characteristics: Purified IgG

Purification: Purified

Immunogen: Balculovirus expressed (Recombinant) p85 beta subunit of bovine PI-3 kinase.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-PIK3R2 antibody (ABIN2476135)

Brehme, Hantschel, Colinge, Kaupe, Planyavsky, Köcher, Mechtler, Bennett, Superti-Furga: "Charting the molecular network of the drug target Bcr-Abl." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 18, pp. 7414-9, (2009) (PubMed).

Hale, Batty, Downes, Randall: "Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation." in: The Journal of biological chemistry, Vol. 283, Issue 3, pp. 1372-80, (2008) (PubMed).

Ehrhardt, Wolff, Pleschka, Planz, Beermann, Bode, Schmolke, Ludwig: "Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses." in: Journal of virology, Vol. 81, Issue 7, pp. 3058-67, (2007) (PubMed).

Target Details for PIK3R2

Target: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Alternative Name: pi-3 KINASE p85 SUBUNIT beta

Gene ID: 5296, 18709, 29741

UniProt: O00459, O08908, P23726, Q63788

Pathways: VEGF Signaling, BCR Signaling