DDX58 antibody

Catalog No. ABIN2476364

Cited in 3+ publications. The Rabbit Polyclonal anti-DDX58 antibody (ABIN2476364) specifically detects DDX58 in WB and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DDX58 antibody (ABIN2476364)

Target: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX58 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DDX58 Antibody

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Characteristics: Purified IgG

Purification: Purified

Immunogen: Human GST-tagged RIG-1 protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References for anti-DDX58 antibody (ABIN2476364)

Satoh, Wada, Yajima, Imaizumi, Yagihashi: "Tumor microenvironment and RIG-I signaling molecules in Epstein Barr virus-positive and -negative classical Hodgkin lymphoma of the elderly." in: Journal of clinical and experimental hematopathology : JCEH, Vol. 54, Issue 1, pp. 75-84, (2014) (PubMed).

Akira, Uematsu, Takeuchi: "Pathogen recognition and innate immunity." in: Cell, Vol. 124, Issue 4, pp. 783-801, (2006) (PubMed).

Yoneyama, Kikuchi, Natsukawa, Shinobu, Imaizumi, Miyagishi, Taira, Akira, Fujita: "The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses." in: Nature immunology, Vol. 5, Issue 7, pp. 730-7, (2004) (PubMed).

Target Details for DDX58

Target: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Alternative Name: RIG-I

Gene ID: 23586

UniProt: O95786

Pathways: Activation of Innate immune Response, Hepatitis C