SIGLEC-5,SIGLEC-14 antibody (FITC)

Catalog No. ABIN2476480

This Mouse Monoclonal antibody specifically detects in FACS. It exhibits reactivity toward Human and Chimpanzee and has been mentioned in 2+ publications.

Quick Overview for SIGLEC-5,SIGLEC-14 antibody (FITC) (ABIN2476480)

Target: SIGLEC-5,SIGLEC-14

Reactivity: Human, Chimpanzee

Host: Mouse

Clonality: Monoclonal

Conjugate: FITC

Application: Flow Cytometry (FACS)

Clone: 1A5

Product Details

Cross-Reactivity: Chimpanzee

Characteristics: Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC)

Immunogen: Siglec-5-Fc protein, consisting of the full-length extracellular region of human Siglec-5, fused with the Fc region of human IgG1.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

References

Nguyen, Hurtado-Ziola, Gagneux, Varki: "Loss of Siglec expression on T lymphocytes during human evolution." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 20, pp. 7765-70, (2006) (PubMed).

Avril, Freeman, Attrill, Clarke, Crocker: "Siglec-5 (CD170) can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation." in: The Journal of biological chemistry, Vol. 280, Issue 20, pp. 19843-51, (2005) (PubMed).

Target Details

Target: SIGLEC-5,SIGLEC-14

Alternative Name: Siglec-5/Siglec-14

Gene ID: 8778, 100049587

UniProt: O15389, Q08ET2